Imuran tablet 50Mg 100 Tab

Imuran tablet 50 mg 100 Tablets

Azathioprine

Antagonizes purine metabolism and may inhibit synthesis of DNA, RNA, and proteins. May also interfere with cellular metabolism and inhibit mitosis.

Indications:

•Renal transplantation: Adjunctive therapy in prevention of rejection of kidney transplants

• Active rheumatoid arthritis.

Points of interest:

• Swallow whole Tablets with full glass of water.

• To reduce stomach upset, take this tablet with food.

• This medication may increase skin sensitivity to sun light, avoid excessive sun exposure and use high SPF sunscreen.

How to use:

As per as direction of doctor.

Active Ingredients:

Azathioprine.

Side effects:

• Leukopenia, thrombocytopenia.

• Fever.

• Nausea, vomiting, diarrhea.

Cautions:

• Monitor for toxicity weekly then every 3 months thereafter.

• Patients must immediately report any signs of infection, bruising, bleeding or any manifestation of bone marrow depression.

• Azathioprine is hepatotoxic and liver function tests should be routinelymonitored.

• Patient should stop treatment if jaundice becomes apparent.

• Caution is required in patients with renal or hepatic impairment.

• Infections such as chickenpox may become severe during treatment.

Interactions:

• ACE inhibitors: increased risk of anaemia when azathioprine is given with Enalapril or Captopril especially in renal impairment.

• Allopurinol: increases plasma levels and toxicity of azathioprine.

• Coumarins: the concomitant use reduces the anti-coagulant effect ofcoumarins.

Quantity:

100 Tablets.

How to store:

Keep at room temperature.