Diclofast 50 mg 20 Tablets
Reversibly inhibits cyclooxygenase-1 and 2 (COX-1 and 2) enzymes, which results in decreased formation of prostaglandin precursors; has antipyretic, analgesic, and anti-inflammatory properties.
• Arthritis conditions: rheumatoid arthritis, osteoarthritis, acute gout.
• Migraine attacks.
• Acute musculoskeletal disorders and trauma such as tendinitis, tenosynovitis, and relief of pain in fractures.
• Control of pain and inflammation in orthopedic, dental, and other minor surgery.
Points of interest:
• Do not take aspirin for pain relief while using this medication.
• Do not take this medication if you are dehydrated, due to severe vomiting or diarrhea.
• Stop this medication and tell your doctor immediately if you develop swollen ankles, difficulty in breathing, chest pain, black stools, or dark vomit.
How to use:
1 tablet every 8 hours after meals.
• GI ulceration or bleeding.
• Raised liver enzymes.
• Elderly, Allergic disorders, Coagulation defects, Cardiac Impairment, history of cardiac failure
• lowest effective dose and shortest duration of action is given to patients having cardiovascular diseases.
• Should not be given to patients with a history of GI diseases.
• Patients with GI disorders and need to have NSAID should be offered a gastroprotective
drugs and must be closely monitored.
• Bronchospasm may be precipitated in patients suffering from or with a previous history of bronchial asthma or allergic disease.
• Contraindicated in patients with moderate to severe renal disease and severe hepatic impairment.
• Anticoagulants: avoid concomitant use with IV diclofenac. Increased risk of hemorrhage
• Cyclosporine: increases the plasma concentration of diclofenac. Reduce dose to half
• Methotrexate: diclofenac reduces the excretion of methotrexate
• Tacrolimus: Nonsteroidal Anti-Inflammatory drugs may enhance the nephrotoxic effect of tacrolimus.
How To Store: